According to Frontline research data, Frontline Plus is an effective method of flea and tick control in kittens, killing 100 percent of fleas within 12 hours of application. Prior to using Frontline products on kittens, be sure to learn the safety guidelines for applying that product to your kitten.
Frontline Spray can be used on kittens from the age of 2 days old. From 2 days old until 8 weeks, this is the only product that Frontline recommends for flea and tick control in kittens. Frontline Spray should be applied to the kitten's skin—underneath the fur—every three weeks for the most effective flea control possible. Frontline Spray eliminates only existing flea or tick infestations; new flea or ticks may appear if the kitten is exposed to either again.
Frontline Plus contains active ingredient fipronil, which kills fleas and ticks, and an insect growth regulator (IGR) called S-methoprene that kills the eggs and larvae. This Frontline formula can be used on kittens who are 8 weeks old or older. According to Frontline research studies conducted in 2011, Frontline Plus is effective as both a flea and tick killer and a preventative. Frontline recommends that the product be applied once every 30 days for maximum benefit.
Frontline Top Spot
Frontline Top Spot contains the same active ingredient as Frontline Plus but lacks its IGR component. It is therefore less effective at long-term flea and tick control, but is as effective as Frontline Plus in terms of eliminating infestations. As with Frontline Plus, Top Spot can be used on kittens 8 weeks or older. Frontline recommends that the product be applied one time every 30 days for maximum benefit.
Frontline recommends that pet owners allow around 24 hours after Frontline product application—or until the area of application is completely dry—before bathing kittens or allowing them to get wet. Frontline should not be applied to wet fur or skin; it is recommended that the kitten be completely dry prior to application. Although reactions are rare, some pets may experience sensitivity at the site of Frontline application. If kittens show any signs of sensitivity following Frontline product application, Frontline recommends that pet owners contact their veterinarian for guidance.